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More recently, a long-acting exendin-4-based analog bound to the Fc portion of immunoglobulin G (IgG) known as efpeglenatide is under clinical development, and would also be suitable for a once-weekly injection [8,9]

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Liraglutide dosage needs continuous monitoring in patients with hepatic or renal impairment, as the medication can cause acute renal failure and exacerbate end-stage renal disease

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