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GLP-1 receptor agonists and delayed gastric emptying: implications for invasive cardiac interventions and surgery - PMC

doi: 10.1210/jc.2003-031328 [DOI] [PubMed] [Google Scholar] 114

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The first clinical candidate for a small-molecule GcgR antagonist was MK-0893 in which 80 mg daily treatment over 12-weeks demonstrated considerable efficacy in reducing fasted plasma glucose by − 34% and HbA1c by − 1.5% relative to placebo [74]