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Desensitization and phosphorylation of the glucagon-like peptide-1 (GLP-1) receptor by GLP-1 and 4-phorbol 12-myristate 13-acetate
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These medications are synthetic analogs or mimetics of human GLP-1 that resist degradation by the enzyme dipeptidyl peptidase-4 (DPP-4), allowing for prolonged therapeutic action