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As GLP-1 receptor agonists move into wider use for diabetes and weight management, many primary care clinicians are discovering that prescribing the medication is only half the challenge. The other half lies
The initial modest reduction at three months (−0.357 kg/m 2 , 95% CI [−0.687, −0.027], p=0.03) evolved into more decrements at subsequent time points
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The standard protocol in clinical trials escalated doses every 4 weeks
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