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“Based on the significant unmet need in Alzheimer’s disease as well as a number of indicative data points, we felt we had a responsibility to explore semaglutide’s potential, despite a low likelihood of success,” Martin Holst Lange, chief scientific officer at Novo Nordisk said in a press release
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So there is a real but early human signal, not a guaranteed effect, and it appears to matter most for people whose Akkermansia levels are low to begin with
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