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The experimental data from rats suggest that the inhibitory effect of GLP-1 on gastric motor function is mediated by the afferent vagal nerve, through interaction with GLP-1Rs located in vagal afferent fibers that transmit sensory signals to the brain (161)
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Studies in rodent models have consistently demonstrated that GLP-1 receptor agonists reduce the consumption of multiple addictive substances — not just alcohol
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