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Metsera Reports Highly Competitive Results from Ongoing Trial of Novel, Potential Once-Monthly Injectable GLP-1 Receptor Agonist MET-097 - BioSpace

[DOI] [PMC free article] [PubMed] [Google Scholar] 112.Clinical Review Report: Semaglutide (Ozempic): (Novo Nordisk Canada Inc.): Indication: For the Treatment of Adult Patients with Type 2 Diabetes Mellitus to Improve Glycemic Control, in Combination with Metformin (Second-Line Treatment), and in Combination with Metformin and Sulfonylurea (Third-Line Treatment) [Internet] Canadian Agency for Drugs and Technologies in Health

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However, although the metabolic efficacy of these emerging agents is clear, their long-term cardiovascular safety profiles remain speculative until the conclusion of ongoing phase 3 trials (Wharton et al., 2025)