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J Clin Invest (2008) 118(11):3693–700.10.1172/JCI36461 28 WuTZhaoBRBoundMJChecklinHLBellonMLittleTJet alEffects of different sweet preloads on incretin hormone secretion, gastric emptying, and postprandial glycemia in healthy humans

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Looking forward, the GLP-1 drugs we study (semaglutide, tirzepatide, and emerging oral formulations like orforglipron) are likely only the beginning of a new wave of chronic therapies for conditions like obesity, heart failure, and even kidney disease