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Dedicated research is essential to discern a concrete causal relationship, and this need is further accentuated by the potential for confounding variables not accounted for in the FAERS database, including the disease’s severity, comorbidities, and concurrent medication regimens
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Liraglutide and dulaglutide, as GLP-1R agonists, can improve AD-related cognitive dysfunction by inhibiting tau protein hyperphosphorylation and NFTs formation through activation of the protein kinase B/glycogen synthase kinase 3 beta (Akt/GSK-3β) signaling pathway (Shu et al., 2019
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