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For Study 3, the primary efficacy parameters were mean percent change in body weight from randomization to Week 56, the percentage of patients not gaining more than 0.5% body weight from randomization (i.e., after run-in) to Week 56, and the percentage of patients achieving greater than or equal to 5% weight loss from randomization to Week 56
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It is not recommended in patients with a history of thyroid tumors and endocrine neoplasias
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